Generation of insulin-secreting cells from human embryonic stem cells
نویسندگان
چکیده
منابع مشابه
differentiation of human embryonic stem cells into insulin- secreting cells
introduction: type i diabetes mellitus is caused by autoimmune destruction of the insulin-producing β-cells. a new potential method for curing the disease is transplantation of differentiated insulin- secreting cells from human embryonic stem cells. methods: human embryonic stem cell lines (royan h1) were used to produce embryoid bodies. differentiation carried out by growth factor-mediated sel...
متن کاملin vitro differentiation of insulin secreting cells from mouse bone marrow derived stage-specific embryonic antigen 1 positive stem cells
background: bone marrow has recently been recognized as a novel source of stem cells for the treatment of wide range of diseases. a number of studies on murine bone marrow have shown a homogenous population of rare stage-specific embryonic antigen 1 (ssea-1) positive cells that express markers of pluripotent stem cells. this study focuses on ssea-1 positive cells isolated from murine bone marro...
متن کاملDifferentiation of Mouse Embryonic Stem Cell into Insulin-Secreting Cell
Purpose: Differentiation of mouse embryonic stem cells into Insulin secreting endocrine cells. Materials and Methods: In this study, Royan B1 mouse embryonic stem cell (derived from C57BL/6 mouse) were used. In directed differentiation method, embryonicstem cells after embryoid bodies formation were differentiated into insulin secreting cells. Nestin positive cells were obtained after culture ...
متن کاملDifferentiation of human embryonic stem cells into neurons
Human embryonic stem (ES) cells are undifferentiated pluripotent cells derived from the inner cell mass of blastocyst stage embryos. These unique cell lines have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. These cells are capable of forming embryoid bodies (EB) that contain cells from all three embryonic lin...
متن کاملDifferentiation of human embryonic stem cells into neurons
Human embryonic stem (ES) cells are undifferentiated pluripotent cells derived from the inner cell mass of blastocyst stage embryos. These unique cell lines have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. These cells are capable of forming embryoid bodies (EB) that contain cells from all three embryonic lin...
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ژورنال
عنوان ژورنال: Development, Growth and Differentiation
سال: 2006
ISSN: 0012-1592,1440-169X
DOI: 10.1111/j.1440-169x.2006.00867.x